News & Events
Iconic Therapeutics to Present Phase 2a Emerge Trial Results at Miami Meeting

February 9, 2017
South San Francisco, February 9 – – Iconic Therapeutics, a clinical stage biopharmaceutical company dedicated to translating knowledge of Tissue Factor biology into new therapeutics for retinal disease and cancer, announced today that the results of its recently completed EMERGE trial, a Phase 2a randomized, double-masked, multi-dose study of the drug candidate ICON-1 in wet Age-Related Macular Degeneration (AMD), will be presented for the first time at the Angiogenesis, Exudation, and Degeneration meeting in Miami, FL on Saturday February 11. The trial design included assessment of outcomes specifically designed to measure lesion growth and leakage, both hallmarks of disease progression in AMD. The EMERGE trial was a six-month, active-controlled, multi-center study of 88 patients with newly diagnosed disease. Iconic previously completed an 18-subject Phase 1 clinical trial in neovascular AMD, which demonstrated safety and preliminary evidence of potential biologic activity.

According to William Greene, M.D., Chief Executive Officer, “The EMERGE data point to ICON-1’s potential to directly address the limitations of currently approved therapies. While the study was not powered for statistical significance, we saw strong signals of biologic activity that provide a clear rationale for further clinical development. We expect to initiate further studies later this year.”
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